Micro-Spray

Co-flow Spray Dryer/Chiller for very small samples

Set-up

  • Designed for SMALL quantities down to 0.25 to 4000 ml
  • Particle range : 2-100 micron
  • Controlled drop diameter; 2-75 micron
  • Unique air-flow control system
  • Narrow size distribution; D90/d10 < 2,5 for particles above 7 micron
  • High yield even when processing small quantities (85% for 25mg product)
  • Unique Atomising system
  • Bi-Fluid special applications
  • Can handle highly "unstable" temperature sensitive materials
  • Tested materials: protein, peptide, hormone, non-aqueous, bacteria, vaccine components, excipient,...
  • Filtered air, can be heated for SPRAY DRYING or cooled for SPRAY CHILLING
  • Easily dissembled, cleaned, sterilized
  • Flexible design
  • Provide data for scale-up
  • Critical process data : airflow, liquid dosing speed/volume, inlet/outlet air temperature, product temperature, pressure drop over process column/filter/product collection
  • PC/PLC automation package: "real-time"-trending and batch recording in Excel of all critical process data and batch identification

Options

  • Chiller for inlet air
  • different types of spray nozzles
  • different types of dosing pumps
  • 21CFRPart11 compliant software
  • Validation IQ/OQ/SQ,...
  • Integration in Containment isolator
  • Different isolator solutions (Stainless Steel, Polycarbonate, PE,..)

Page last updated : 24-02-2010